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Featuring articles on a randomized closed-loop trial in very young children with diabetes, microbiome therapy for C. difficile infection, secondary prophylaxis for latent rheumatic heart disease, targeting mutant HER2 in non–small-cell lung cancer, urinary sodium and potassium and cardiovascular risk, and on aesthetic distance and empathy; a review…
 
Multisystem inflammatory syndrome in children (or MIS-C) is a serious complication of Covid-19 infection, usually showing up about a month after infection. CDC worked with several hospitals around the U.S. to discern whether vaccination in adolescents would lessen the likelihood of this outcome. A vaccine hadn’t yet been approved, as it now is, for…
 
In this episode of Curbside Consults, we examine the latest guidelines on reassessing the inclusion of race in eGFR equations from the National Kidney Foundation (NKF) and American Society of Nephrology (ASN). We are joined by one of the guideline authors -- Nwamaka Eneanya, Director of Health Equity, Anti-Racism and Community...…
 
A 38-year-old woman with type 2 diabetes has a telemedicine visit after learning that a person with whom she had close contact at an indoor wedding 3 days earlier has tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The woman reports that she is asymptomatic and received a second vaccination against SARS-CoV-2 appro…
 
Featuring articles on the efficacy of mRNA vaccines in U.S. veterans, Covid-19 vaccine effectiveness in New York state, FFR-guided PCI as compared with coronary bypass surgery, an acute myeloid leukemia case after gene therapy for sickle cell disease, cannabis legalization and THC levels in injured drivers, oocytes from stem cells, and a new journa…
 
Featuring articles on eltrombopag in severe aplastic anemia, nivolumab plus LAG-3 blockade in melanoma, the BNT162b2 vaccine against Covid-19 in 5-to-11-year-olds, azithromycin for yaws eradication, and abortion outcomes with unrestricted mifepristone; a review article on snake envenomation; a Clinical Problem-Solving on being confused about confus…
 
Featuring articles on chlorthalidone for hypertension in advanced chronic kidney disease, ticagrelor versus clopidogrel in stroke or transient ischemic attack, dolutegravir in children with HIV-1 infection, angiography after out-of-hospital cardiac arrest, and the 2021 Nobel Prize in Chemistry; a review article on the determination of brain death; …
 
Featuring articles on the effects of a Covid-19 vaccine booster, spesolimab for generalized pustular psoriasis, decentralized molecular testing for tuberculosis, and consultative medicine; a review article on immune and genome engineering as the future of transplantable tissue; a case report of a woman with respiratory failure and altered mental st…
 
In this episode of Curbside Consults, we examine the latest guidelines on the management of Clostridiodes difficile (C. difficile) infection. This year, updated guidelines were developed by the Infectious Diseases Society of America and Society for Healthcare Epidemiology of America, as well as the American College of Gastroenterology. Here, we...…
 
Featuring articles on daprodustat in patients undergoing dialysis and in those not undergoing dialysis, chemotherapy in node-positive breast cancer, a phase 3 trial of the ChAdOx1 nCoV-19 vaccine, vaccine effectiveness among U.S. health care personnel, and a hot and tactile Nobel Prize; a review article on pulmonary arterial hypertension; a case re…
 
Featuring articles on tapinarof cream for psoriasis, dupilumab in children with asthma, the mRNA-1273 vaccine in adolescents, cardiovascular events with finerenone in kidney disease and type 2 diabetes, waning vaccine protection against SARS-CoV-2, and transgenic epidermis in junctional epidermolysis bullosa; a review article on latent tuberculosis…
 
In this episode of Curbside Consults, we examine the latest guidelines on the management of ANCA-associated vasculitis by the American College of Rheumatology (ACR) and Vasculitis Foundation. In doing so, we review the major trials in vasculitis research published during the last 10 years with one of the guideline authors, Dr. Peter...…
 
Featuring articles on debulking surgery in relapsed ovarian cancer, myocarditis after Covid-19 mRNA vaccine, edoxaban for atrial fibrillation with TAVR, milvexian for the prevention of venous thromboembolism, REGEN-COV in outpatients with acute SARS-CoV-2 infection, and a font of protein structures; a review article on spontaneous intracranial hypo…
 
Featuring articles on spinal or general anesthesia for hip surgery, HIF-2α inhibition in von Hippel–Lindau disease, live birth after genetic testing for aneuploidy, belzutifan in the Pacak–Zhuang syndrome, and on responsible innovation in reproductive medicine; a review article on osteosarcoma; a case report of a man with pain and erythema of the l…
 
Featuring articles on hematopoietic gene therapy for Hurler syndrome, sotrovimab for early Covid-19, convalescent plasma for high-risk Covid-19, gene therapy for hemophilia A, parathyroid hormone resistance, and on hunger and mood; a review article on salt handling and blood pressure; a case report of a woman with pain in the left upper quadrant an…
 
Featuring articles on alteplase followed by endovascular treatment for stroke, sacubitril–valsartan in acute myocardial infarction, pembrolizumab in advanced cervical cancer, genome sequencing in health care, and screening for cervical cancer; a review article on pollution and the heart; a case report of a man with altered mental status and new ons…
 
Featuring articles on new equations for estimating GFR without race, BNT162b2 vaccine at 6 months of follow-up, efficacy of the mRNA-1273 vaccine at the end of the blinded phase, providing grist for antitumor immunity; and continuity, fragmentation, and Adam Smith; a review article on peritoneal dialysis; a Clinical Problem-Solving describing a cop…
 
Featuring articles on dual antiplatelet therapy in patients at high bleeding risk, itepekimab in moderate-to-severe asthma, risankizumab in severe asthma, and vaccine-induced thrombocytopenia and thrombosis; a review article on abdominal aortic aneurysms; a case report of a man with painful mouth ulcers; and Perspective articles on uncomfortable tr…
 
Kiarri Kershaw has written a simple letter in JACC — the Journal of the American College of Cardiology. The letter conveys a strong message: health inequities don’t act uniformly across one’s lifetime. Her examination of Black versus white mortality from all causes and from cardiovascular causes with the use of age-specific data shows places in the…
 
In this episode of Curbside Consults, we discuss how patients and physicians are using the latest technology to manage diabetes mellitus. We are joined by Prof. Derek O'Keeffe, Consultant Physician (Endocrinologist) at University Hospital Galway Ireland and Professor...
 
An internist at Massachusetts General Hospital, Dr. Joseph Betancourt also runs their program on equity and community health. In this, the final entry in our four-interview exploration of race and clinical equity, Betancourt talks about the need for medical institutions to pay attention to what’s happening in their patients’ communities. To that en…
 
Dr. Sheares talks about her experience with inequities. She believes that clinicians should aspire to be students of their patients as well as of the pathophysiology of the diseases their patients present with. Listen in. Running time: 20 minutes The post Podcast 277: Race and clinical equity — know your patients — a conversation with Karen Dorsey …
 
In this, our second conversation on race and clinical equity, Dr. Karol Watson of UCLA offers her observations on what she’s observed as a cardiologist trying to deal with treatment plans for patients who’ve lost their health insurance or have had to go to a plan that doesn’t cover what’s needed. She reminds us that tagging people as “non-compliant…
 
We’ve conducted a set of four interviews with physicians on the topic of race and clinical equity. The conversations center not so much on their published research, but on the roles that these physicians take in their organizations and, in addition, the stories they tell about their own experiences. Our first is with Dr. Kimberly Manning, who’s a p…
 
In this episode of Curbside Consults, we discuss the diagnosis and management of primary, secondary, and tertiary hyperparathyroidism with Dr. O.P. Hamnvik, who is an endocrinologist and educator at the Brigham and Women’s Hospital in Boston and the NEJM Group...Por NEJM Group
 
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