How a Probiotic Strain Calms Your Body & Brain Stress – Kiran Krishnan, Ph.D. : 927


Manage episode 326021917 series 1412085
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SPECIAL OFFER FOR BULLETPROOF RADIO LISTENERS: Go to You’ll find their new line, Joot, and their new Just Calm probiotic for stress management and mood support. Just Calm features the proprietary “psychobiotic” strain BL 1714™ combined with brain-nourishing B vitamins. You’ll also find other products that tackle gut health and inflammation. Use code ASPREY to get a 15% off discount.


…you’ll learn about a strain of probiotics called psychobiotics. This strain shows promising effects on stress relief, anxiety, mood, sleep and other important gut-brain axis connections.

Microbiologist Kiran Krishnan, Ph.D., explores the human microbiome and how it functions so you can have better gut health. He has an extensive research background in the fields of molecular medicine and microbiology. His particular expertise lies in gut commensal spore bacteria microbiology.

He’s been a guest on the show before to educate listeners about probiotics and the connections between your microbiome, inflammation and immune function. This time, he’s sharing exciting research about a probiotic strain that’s tackling the gut-brain axis, called Bifidobacterium longum 1714™.

Kiran says, “One really important message that I want people to really wrap their heads around and understand when we're talking about the gut-brain axis is, of course, the gut. A healthy gut is incredibly supportive to the brain. It supports the brain in a number of really important critical functions like recovery, for example, or production of serotonin and dopamine and all these important neurotransmitters, but on the other end of the spectrum, an unhealthy gut is not only not supportive, but it's arguably one of the most toxic things for the brain.”

Big topics covered in this episode include:

  • Basic mechanisms by which the gut microbiome can influence neurochemicals and brain inflammation
  • The gut-brain connection as it relates to stress coping and mental health
  • How cortisol and interleukin 6 drive stress response and inflammation in your whole body
  • Variables that can cause a breakdown or dysfunction in the psychobiome
  • Therapeutic interventions, including psychobiotics that can help correct gut-brain axis dysfunction

Kiran’s great at explaining the science so you clearly understand what the studies mean and can apply new knowledge to your own biology. He also partners with Just Thrive Health on product research and development.

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