How can we, humans, look at our relationship to nature differently? In season three of Going Wild, on top of stories about animals, we invite you to journey through the entire ecological web — from the tiniest of life forms to apex predators — alongside the scientists, activists and adventurers who study it. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals in their natural habitats all over the world for years. Our award-winning podcast takes you inside the hidde ...
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🧬 Mark Kotter - bit.bio - Part 4 | Democratizing Access to Cells & the Evolution of bit.bio | A Financial Journey from Angel Investment to IPO | Building a Tech Bio Platform & Mark’s 10-Year Vision
MP3•Home de episódios
Manage episode 425889133 series 3461709
Conteúdo fornecido por Jon Chee. Todo o conteúdo do podcast, incluindo episódios, gráficos e descrições de podcast, é carregado e fornecido diretamente por Jon Chee ou por seu parceiro de plataforma de podcast. Se você acredita que alguém está usando seu trabalho protegido por direitos autorais sem sua permissão, siga o processo descrito aqui https://pt.player.fm/legal.
Part 4 of 4.
My guest for this week’s episode is Mark Kotter, neurosurgeon, stem cell biologist, and CEO and founder of bit.bio. He has also been a professor and researcher at Cambridge for more than 15 years.
Bit.bio is an award-winning human synthetic biology company providing human cells for research, drug discovery, and cell therapy. The company applies a patented safe harbor gene targeting approach to inducibly express transcription factor combinations that reprogram human-induced pluripotent stem cells into highly defined and mature human cell types. Bit.bio spun out of the University of Cambridge in 2016 and has since raised approximately $200 million from Arch Ventures, Foresight Capital, Milky Way, Charles River Laboratories, National Resilience, Tencent, and Pulau Capital, among others.
Mark is also the co-founder of Meatable, scientific founder and chairman of rejuvenation startup clock.bio, and co-founder and trustee of Myelopathy.org, the first charity dedicated to a common yet often overseen condition causing a slow-motion spinal cord injury. His diverse experience as an academic and serial entrepreneur offers a wealth of insights aspiring scientist founders can draw from.
Join us this week and hear about:
- The evolution of bit.bio and their mission to democratize access to human cells and therapies
- Building a solid infrastructure and hiring the right people
- The early hurdles of securing funding and managing co-founder dynamics and bit.bio’s financial journey from angel investments to institutional funding
- Mark’s plans to take the company public
Please enjoy my conversation with Mark Kotter.
Timestamps
00:28 Intro
01:52 Democratizing access to cells, the core mission of bit.bio
04:06 A new paradigm of creating batches of cells
06:26 Creating a new market out of a disruptive product
09:20 The business initiatives at bit.bio and Mark’s driving philosophies
11:28 The journey of new modality platforms like bit.bio’s & the IP landscape
15:02 Building the infrastructure and engine powering bit.bio, finding the right people
23:05 Financing bit.bio early on and their financial journey from a small, scrappy lab
26:56 Raising larger funds from institutional investors, bit.bio’s Series A and B
28:56 Mark’s future plans and 10-year vision for bit.bio
31:16 The 2-year vision, what will happen at bit.bio in the near future
34:16 Shout outs and advice to 21-year old self
36:05 Outro
Find Our Guest, Mark Kotter, at these links:
Find Our Host, Jon Chee, at these links:
Social & Website
LinkedIn: https://www.linkedin.com/company/excedr/
Youtube: https://www.youtube.com/@excedr
Instagram: https://www.instagram.com/excedr_inc
Twitter: https://twitter.com/ExcedrInc
Facebook: https://www.facebook.com/excedr
TikTok: https://www.tiktok.com/@excedr
Topics Mentioned:
bit.bio https://www.bit.bio/
Charles River Laboratories https://www.criver.com/
Meatable https://meatable.com/
University of Cambridge https://www.cam.ac.uk/
GMP (Good Manufacturing Practice) https://www.excedr.com/resources/gmp-vs-glp-whats-the-difference
Intellectual Property Strategy in Biotech https://www.excedr.com/resources/intellectual-property-strategy-for-biotechs
Patents in Biotech https://www.excedr.com/resources/intellectual-property-rights-for-biotechs
Partnerships in Biotech https://www.excedr.com/blog/how-biotech-partnerships-support-research
Genetic Engineering https://medicine.missouri.edu/centers-institutes-labs/health-ethics/faq/gene-therapy
People Mentioned:
Shinya Yamanaka https://en.wikipedia.org/wiki/Shinya_Yamanaka
Kathryn Penkus Corzo https://www.linkedin.com/in/kathryn-penkus-corzo/
The Biotech Startups Podcast is handcrafted by our friends over at: fame.so
83 episódios
MP3•Home de episódios
Manage episode 425889133 series 3461709
Conteúdo fornecido por Jon Chee. Todo o conteúdo do podcast, incluindo episódios, gráficos e descrições de podcast, é carregado e fornecido diretamente por Jon Chee ou por seu parceiro de plataforma de podcast. Se você acredita que alguém está usando seu trabalho protegido por direitos autorais sem sua permissão, siga o processo descrito aqui https://pt.player.fm/legal.
Part 4 of 4.
My guest for this week’s episode is Mark Kotter, neurosurgeon, stem cell biologist, and CEO and founder of bit.bio. He has also been a professor and researcher at Cambridge for more than 15 years.
Bit.bio is an award-winning human synthetic biology company providing human cells for research, drug discovery, and cell therapy. The company applies a patented safe harbor gene targeting approach to inducibly express transcription factor combinations that reprogram human-induced pluripotent stem cells into highly defined and mature human cell types. Bit.bio spun out of the University of Cambridge in 2016 and has since raised approximately $200 million from Arch Ventures, Foresight Capital, Milky Way, Charles River Laboratories, National Resilience, Tencent, and Pulau Capital, among others.
Mark is also the co-founder of Meatable, scientific founder and chairman of rejuvenation startup clock.bio, and co-founder and trustee of Myelopathy.org, the first charity dedicated to a common yet often overseen condition causing a slow-motion spinal cord injury. His diverse experience as an academic and serial entrepreneur offers a wealth of insights aspiring scientist founders can draw from.
Join us this week and hear about:
- The evolution of bit.bio and their mission to democratize access to human cells and therapies
- Building a solid infrastructure and hiring the right people
- The early hurdles of securing funding and managing co-founder dynamics and bit.bio’s financial journey from angel investments to institutional funding
- Mark’s plans to take the company public
Please enjoy my conversation with Mark Kotter.
Timestamps
00:28 Intro
01:52 Democratizing access to cells, the core mission of bit.bio
04:06 A new paradigm of creating batches of cells
06:26 Creating a new market out of a disruptive product
09:20 The business initiatives at bit.bio and Mark’s driving philosophies
11:28 The journey of new modality platforms like bit.bio’s & the IP landscape
15:02 Building the infrastructure and engine powering bit.bio, finding the right people
23:05 Financing bit.bio early on and their financial journey from a small, scrappy lab
26:56 Raising larger funds from institutional investors, bit.bio’s Series A and B
28:56 Mark’s future plans and 10-year vision for bit.bio
31:16 The 2-year vision, what will happen at bit.bio in the near future
34:16 Shout outs and advice to 21-year old self
36:05 Outro
Find Our Guest, Mark Kotter, at these links:
Find Our Host, Jon Chee, at these links:
Social & Website
LinkedIn: https://www.linkedin.com/company/excedr/
Youtube: https://www.youtube.com/@excedr
Instagram: https://www.instagram.com/excedr_inc
Twitter: https://twitter.com/ExcedrInc
Facebook: https://www.facebook.com/excedr
TikTok: https://www.tiktok.com/@excedr
Topics Mentioned:
bit.bio https://www.bit.bio/
Charles River Laboratories https://www.criver.com/
Meatable https://meatable.com/
University of Cambridge https://www.cam.ac.uk/
GMP (Good Manufacturing Practice) https://www.excedr.com/resources/gmp-vs-glp-whats-the-difference
Intellectual Property Strategy in Biotech https://www.excedr.com/resources/intellectual-property-strategy-for-biotechs
Patents in Biotech https://www.excedr.com/resources/intellectual-property-rights-for-biotechs
Partnerships in Biotech https://www.excedr.com/blog/how-biotech-partnerships-support-research
Genetic Engineering https://medicine.missouri.edu/centers-institutes-labs/health-ethics/faq/gene-therapy
People Mentioned:
Shinya Yamanaka https://en.wikipedia.org/wiki/Shinya_Yamanaka
Kathryn Penkus Corzo https://www.linkedin.com/in/kathryn-penkus-corzo/
The Biotech Startups Podcast is handcrafted by our friends over at: fame.so
83 episódios
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