Instigators of Change is a Khosla Ventures podcast that explores innovative ideas, the people who come up with them, and those who invest in them. Our guests are the outliers, creators, mavericks — those who imagine differently. They build companies that alter transportation, retail, food, energy, entertainment, space. And when they succeed, we cannot imagine life without them. Tune in to hear about non-obvious ideas from inspiring people. The podcast is hosted by Kara Miller, former host of ...
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How to Conquer Imposter Syndrome, and Become a Tech CEO
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Shellye Archambeau has encountered a lot of obstacles in life, but her ability to navigate around them has proved almost superhuman. Archambeau talks about deciding - as a teenager - that she wanted to be a CEO, and how she navigated the business world to make that happen. How do you deal with a company that’s not paying you enough? That won’t prom…
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Dheeraj Pandey Wants to Change CRM. Can He?
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When Dheeraj Pandey co-founded the cloud computing company Nutanix in 2009, the economy was shaky. Housing was turbulent. And interest rates had moved dramatically. Sound familiar? Nutanix would grow into a multibillion dollar company, and now, Pandey is back at the start-up game. He’s trying to change CRM, though it’s a tough time to be challengin…
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Why entrepreneurs ignore an aging America - at their peril
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After tennis great Serena Williams announced her retirement from tennis, she tweeted out an article from Joseph Coughlin, head of the MIT AgeLab. Williams said she wasn’t retiring - she was “forever evolving.” And Coughlin believes that Williams’ sentiment is a sign of the times. Average Americans are getting older. They’re living longer. They want…
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Jeff Wilke: From Amazon Exec to Rebuilding American Manufacturing
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When Jeff Wilke left Amazon in 2021, where - since 2016 - he had served as CEO of Amazon Worldwide Consumer, his next chapter could have focused on rest and relaxation. After all, Wilke had been at Amazon for more than 20 years, and had seen it grow from a modest-sized bookseller to a worldwide behemoth. But Wilke believes the American economy - an…
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What Evidence Shows About Who Really Succeeds in Business
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You might call Ethan Mollick a man obsessed. And he probably wouldn’t mind. Because Mollick - a high-profile professor at The Wharton School - is obsessed with data, which dispels a lot of the myths around startups. Like: Do twenty somethings have the most successful startups? Nope, it’s forty-somethings. Are teams more successful than solo founder…
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Siddhartha Mukherjee and Anand Parikh On A New Way To Fight Cancer
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More than 50 years ago, President Nixon announced a moonshot to cure cancer. But the cure never came. More than half a million Americans still die from cancer every single year. Pulitzer-Prize-winning author and cancer physician Siddhartha Mukherjee says that, in some ways, the scientific community has failed - and it must embrace new approaches. O…
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Why Nextdoor CEO Sarah Friar Took A Big Career Risk
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When Sarah Friar quit as the CFO of Square, CEO Jack Dorsey wasn't thrilled. But she felt compelled to take the leap. Friar explains why she left, and how her childhood in a conflict-plagued part of Northern Ireland factored into the decision. Plus, if you're building a company now, how should you navigate this tricky economic environment? How shou…
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From Cute Cats to Political Upheaval: How YouTube Changed The World
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In 2005, a small company began offering up a way to post amateur videos on the web. YouTube operated on a shoestring, with its founders maxing out credit cards, and debating what the company was really about. The next year, Google - sensing that YouTube would be a powerful force in search - acquired them. This week, author Mark Bergen tells the sto…
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In the early 2000s, a baby clothes salesman was about to strike it big. His name was Adam Neumann, and his rise - and fall - has a lot to teach both founders and funders about why a company can go off the rails. Neumann's new real estate venture, Flow, recently got a $350 million investment from Andreessen Horowitz. We thought it'd be a good time t…
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How one VC navigates today's volatility (Rebroadcast)
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Financial markets have been up and down enough to make anyone seasick. And if you're starting a company - or investing in one - it's an uncertain time. In one of our most popular episodes of the last few months, Samir Kaul - a founding partner of Khosla Ventures - talks about how this volatility compares to the downturns of 2001 and 2008, why he's …
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Why Big Money Makes Big Bets (Rebroadcast)
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This month, as we highlight some of our favorite episodes, we take a look at an industry that has altered the economic fortunes of the world over the last 50 years: venture capital. It has brought us game-changing medicines and life-reordering tech. But not without controversy. And today’s venture capitalists want to fund companies that alter how w…
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How AI destroys businesses... and creates new ones (Rebroadcast)
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This summer, we're revisiting some of our favorite shows. Including this discussion with Harvard Business School professor Karim Lakhani, which reflected Lakhani's view that almost every company is now an AI company. Even if founders and CEOs aren't always thrilled to hear it. In fact, he says, artificial intelligence is upending the way business i…
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Can Batteries Solve Everything? (Rebroadcast)
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As the summer - and lots of record-setting heat - drags on, you might wonder how we can slow global warming. But, even for a scientist and entrepreneur like Jay Whitacre, who has spent decades thinking about how to get Americans to embrace cleaner energy... it’s complicated. Should you, for example, buy an all-electric car? Actually, it depends on …
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Ben Horowitz on Building Company Culture
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Ben Horowitz isn’t afraid to pick favorites when it comes to great CEOs. Like Andy Grove, the former head of Intel. Grove didn’t put up with any nonsense, Horowitz says, because he was singularly focused on what it takes to achieve and maintain greatness. In our next show from KV’s CEO Summit, Horowitz - the co-founder of the venture capital firm A…
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Star In a Bottle: Can Fusion Solve Our Energy Crisis?
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Imagine if we could harness the power of a star, right here on Earth. Our energy challenges, as we know them, would disappear. That’s the promise of fusion technology, a way of generating electricity that scientists have been working on for decades, but have never quite cracked. Are we any closer in 2022? Commonwealth Fusion Technology, a venture-b…
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How A Tough 2022 Could Reshape Biotech
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From massive supply chain issues to wary investors, 2022 is turning out to be a tough year for biotech. But it's also a sector that's reshaping our lives, as we saw during the pandemic. So what are the most exciting opportunities in biotech right now? And where are the pitfalls? Cellino co-founder Nabiha Saklayen and Khosla Ventures partner Alex Mo…
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Vinod Khosla’s American Story (Rebroadcast)
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On a week when we celebrate American indepedence, we revisit our conversation with venture capitalist Vinod Khosla. Khosla talks about coming to the U.S. and what it took to succeed here. Then, we look at the environmental implications when billions of people around the world want to live like Americans. Plus, Khosla explains why he’s so interested…
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Sure, Roger Martin used to run a business school. But that doesn't stop him from questioning the way we train captains of industry. In fact, he argues, many business leaders don't realize that we're not just locked in a struggle between capital and labor. Now, managing talent may be the most important part of your job as a leader. From Julia Robert…
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How one VC navigates today's volatility
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Financial markets have been up and down enough to make anyone seasick. And if you're starting a company - or investing in one - it's an uncertain time. Samir Kaul, a founding partner of Khosla Ventures, talks about how this volatility compares to the downturns of 2001 and 2008, why he's not panicking, and how companies should navigate this new real…
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MIT's Angela Belcher on cancer, green synthesis, and getting inventions to market
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About a decade ago, when the President of MIT approached Angela Belcher about doing cancer research, Belcher turned her down. After all, Belcher is a materials and biological engineer who had done lots of work on environmental sustainability. But cancer research? That was an area she didn't feel she could contribute to. And then she realized that a…
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Should you be radically candid at work?
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Kim Scott admits she has made some huge mistakes as a boss - mistakes that made her kind of obsessed with becoming a better manager. She's also learned a thing or two from being managed by Sheryl Sandberg, and from teaching managers at Apple to lead. She argues that if you don’t know what you’re doing as a leader, productivity will suffer. The team…
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Patrick Brown makes burgers for a living, but he’ll tell you without hesitation: he has no interest in making burgers. So how did a Stanford biochemist - who happily studied cells in a lab - end up trying to revolutionize fast food? He talks to us about why he felt compelled to quit his job, how he thinks burgers could help save us from economic an…
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You want to do what’s right for the planet. So you buy an all-electric car. Right? Well... not always. Jay Whitacre, one of the country’s foremost experts on batteries, tells us why where you live may dictate the answer to that question. Which speaks to the strange moment we're in right now, when it comes to batteries. Whitacre says that getting ba…
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Turning pollution into jet fuel (and yoga pants)
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Sure, lots of business leaders have big dreams. But when Jennifer Holmgren tells you she wants to turn pollution into both jet fuel and yoga pants, she means it. And she's done it. Her company, LanzaTech, has refined a technology to recycle carbon. And, as she explains, they can pull right up to a super-polluting steel mill and start gobbling up th…
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What Smart Companies Know about Working with the Government
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Silicon Valley and Washington, D.C., aren't always two peas in a pod. The "move fast, break things" approach may not square with a cautious-at-all-costs outlook. So if you're a company that needs to work with government regulators, how do you do it? And achieve your goals? Michael Huerta, who ran the FAA and served as U.S. Secretary of Transportati…
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Self-driving seemed like a can’t-miss technology. Smart people were working on it. Money was poured into it. So why, decades later, aren’t you answering your email, while lounging in the backseat of a self-driving car on your daily commute? Sven Strohband, who came early to the world of self-driving cars and is now a partner at Khosla Ventures, say…
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How AI destroys businesses... and creates new ones
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Artificial intelligence is upending the way business is done, and shifting who has the advantage. We talk with Harvard Business School's Karim Lakhani about why traditional models don't work anymore, why some companies are in denial about that, and where the opportunities are now. Plus, thorny questions over data, and China's growing influence over…
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How to Beat Burnout and Master Recruiting
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Data shows that Americans are less happy than they’ve been in 50 years and - no surprise - that has implications for the work we do. Folks building companies are dealing with employees who are burnt out - while often feeling exhausted themselves. So how do you make decisions that really help employees? Jennifer Moss, author of "The Burnout Epidemic…
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Venture capital has drawn both supporters and detractors, as it has altered the economic fortunes of the world over the last 50 years. Today, venture capitalists have some very lofty goals. They want to fund companies that change how we shop, eat, travel, work, and more. Venture capital is revolutionizing China, and coming under fire for a lack of …
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In the early 2000s, a baby clothes salesman was about to strike it big. His name was Adam Neumann, and his rise - and fall - has a lot to teach both founders and funders about why a company can go off the rails. Bestselling authors Maureen Farrell and Eliot Brown join us to talk about how Neumann helped build WeWork, how he attracted tremendous amo…
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On the premiere episode of “Instigators of Change,” we talk with venture capitalist Vinod Khosla about what to watch for - and what to watch out for. Vinod explains why he’s so interested in improbable notions, why he’s failed so often, and what ideas captivate him now. Plus, how can tech help fix the climate crisis? Vinod argues it may be about to…
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Instigators of Change is a Khosla Ventures podcast that explores innovative ideas, the people who come up with them, and those who invest in them. Our guests are the outliers, creators, mavericks — those who imagine differently. They build companies that alter transportation, retail, food, energy, entertainment, space. And when they succeed, we can…
…
continue reading