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Interviews with authors of articles from JAMA Psychiatry. JAMA Psychiatry is an international peer-reviewed journal for clinicians, scholars, and research scientists in psychiatry, mental health, behavioral science, and allied fields. JAMA Psychiatry strives to publish original, state-of-the-art studies and commentaries of general interest to clinicians, scholars, and research scientists in the field. The journal seeks to inform and to educate its readers as well as to stimulate debate and f ...
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Editors at The Lancet Neurology, in conversation with the journal’s authors, explore their latest research and its impact on people’s health, healthcare, and health policy. A monthly audio companion to the journal, this podcast covers a broad range of topics, from sleep habits to amyloid biomarkers in Alzheimer’s, the diagnosis and classification of optic neuritis to treatment of Creutzfeldt-Jakob disease, and more.
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Multiple sclerosis (MS) affects 400,000 Americans and is the leading nontraumatic cause of neurological disability in young adults. Although MS is progressive, it is not fatal, and patients generally have a normal lifespan. However, progressive disability imposes increasing limitations and reduced quality of life for these patients. Newly released consensus guidelines offer neurologists and primary care physicians direction to improve the differential diagnosis and develop strategies to faci ...
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Secular Minority is a eye-opening podcast that looks at the world under the lens of a non-believing Humanist. Atheists, Agnostic, Non-Believers, And Humanists are minorities in this world, let's change that by showing up and speaking out! Secular: A person who does not believe in supernatural realms, beings, or entities, is not religious, or belong to a religious group. Minority: A part of a population differing from others in some characteristics and often subjected to differential treatmen ...
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This bilingual series of podcasts features primarily educational narratives that deal with the different forms of family / domestic / conjugal / intimate partner violence mostly against women, but can also apply to males and two-spirited folks who can use some help in determining whether what they are experiencing is indeed violence, in any form. Upcoming episodes for Season 2 will include : 1) One Indigenous woman's sharing of her personal story of trauma, resilience, and perseverance in th ...
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Cystic fibrosis (CF) is one of the most prevalent global congenital disorders, affecting some 70,000 individuals worldwide and 30,000 children and adults in the United States. While clinical efforts are expanding worldwide to improve diagnostic testing and treatment approaches for this progressive lung disease, targeted therapies for CF against any specific mutation remain elusive. The Cystic Fibrosis in Focus series gathers the latest information from leading medical experts devoted to adva ...
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MedEdTalks - Psychiatry

Vindico Medical Education

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MedEdTalks Psychiatry is an accredited educational podcast for providers to learn more about treating patients with Psychiatry diseases/disorders. Discover all content and topics, by visiting mededtalks.com.
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MedEdTalks - Gastroenterology

Vindico Medical Education

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MedEdTalks Gastroenterology is an accredited educational podcast for providers to learn more about treating patients with Gastroenterology diseases/disorders. Discover all content and topics by visiting mededtalks.com.
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MedEdTalks Neurology is a continuing medical education podcast for physicians to allow them to learn while on the go and obtain CME credits. This show will focus in on multiple sclerosis and includes interviews with Dr. Patricia Coyle from Stony Brook Medical Center, Dr. Claire Riley from Columbia University, Dr. Clyde Markowitz from University of Pennsylvania and Dr. Bruce Cohen from Northwestern University.
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In this week's episode we’ll discuss how CD8+ T-cell differentiation and dysfunction inform treatment response in acute myeloid leukemia; learn more about the effect of ATM germline pathogenic variants on the outcomes in children with ataxia-telangiectasia and hematological malignancies; and discuss the preclinical efficacy of a potent, selective m…
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In this week's episode we’ll discuss a novel tripartite fusion drives treatment resistance in acute promyelocytic leukemia. In some patients with atypical APL, these novel retinoic acid receptor gene fusions result in truncation of the ligand binding domain of the retinoic acid receptor protein, resulting in non-responsiveness to treatment with all…
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Guillain Barre Syndrome (GBS) explained, including GBS pathophysiology and causes, symptoms and how they vary between the GBS subtypes (e.g Miller Fisher, AMAN). Also includes diagnosis and GBS treatment. Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation…
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In this week's episode we’ll discuss the safety and efficacy of pirtobrutinib with or without rituximab in relapsed/refractory CLL; learn more about erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine; and discuss how targeting PKC alpha alleviates iron overload in diabetes and hemochromatosis through …
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In this week's episode we'll discuss outcomes following hematopoietic stem cell transplantation in pediatric patients with Fanconi anemia. Then, we'll learn about how new research shows that the transcription factor Foxo1, commonly associated with glucose metabolism, regulates hepcidin expression and systemic iron homeostasis. Finally, in Latin Ame…
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Prof Jorge Correale and Dr Lilyana Amezcua talk to The Lancet Neurology about their Personal View papers, published in the October 2024 issue, on the differential diagnosis of multiple sclerosis in regions outside North America and Western Europe and in people from minority ethnic or racial backgrounds in North America, northern Europe, and Austral…
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Psoriasis explained, including the different types and treatment options for each. Also includes psoriasis pathophysiology, causes and aggravating factors. Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1 Patreon: https://www.patreon.com/rhesusmedicin…
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In this week's episode we'll discuss HA-1-targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation. Next, we'll learn about how 4D intravital imaging in mice reveals the key role of platelets as a source of procoagulant membranes in hemostasis. Finally, we'll hear about modifications to a common i…
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In this week's episode we’ll discuss the outcomes of younger patients with mantle cell lymphoma experiencing late relapse; learn more about mass spectrometry-based assessment of M-protein in peripheral blood during maintenance therapy in multiple myeloma and discuss in vivo CAR T-cell generation in non-human primates using lentiviral vectors. Featu…
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Introduced by Associate Editor Dr. Thomas Ortel, this bonus episode discusses the Review Series on Factor XI, published in volume 143 issue 15 of Blood Journal. Dr. Ortel is joined by contributing authors Owen McCarty, PhD, Gili Kenet, MD, and David Gailani, MD. Review Series Articles: Introduction to a review series on factor XI Biology of factor …
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A look at Histrionic Personality Disorder, a Cluster B Disorder in the DSM 5, including the main symptoms and traits, as well as the diagnostic criteria. Also includes treatment approach. Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1 Patreon: https…
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In this week's episode we'll learn how cytomegalovirus infection early in life depletes preleukemic cells in a mouse model of B-cell acute lymphoblastic leukemia. After that we'll discuss new research, where GVHD targets organoid-forming bile duct stem cells in a TGF-beta-dependent manner. Conversely, a TGF-beta inhibitor protects these stem cells …
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Understanding Narcissistic Personality Disorder (NPD), including the 9 core signs and symptoms as well as the DSM 5 criteria for diagnosis. Also includes treatment / management options. Free Practice Material: https://app.wisdolia.com/deck/k5eIx6VHKWXwmpbUZGSb?r=DnwHGyl95QQgP3ecVSPDHrFGE0E0qB&ref=rhesusmedicine Consider subscribing on YouTube (if y…
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In this week's episode we'll learn about iron, HFE hemochromatosis, and infections. In this large, population-based study, both high and low levels of plasma iron and transferrin saturation were associated with increased risks of infection. Then, we'll discuss how bispecific antibodies improve CAR T-cell response in B-cell malignancies. In-vitro an…
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Dr Alex Iranzo joins The Lancet Neurology to discuss his recent Review on the association between sleep disorders and Parkinson's disease. The Review is published in the August issue of The Lancet Neurology. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00170-4?dgcid=buzzsprout_icw_podcast_generic_laneur …
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In this week's episode we’ll discuss how immune fitness impacts response to teclistamab in relapsed/refractory multiple myeloma; learn more about a new mechanism of resistance to asciminib conferred by the BCR::ABL1 M244V mutation, and discuss the impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell…
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Understanding sciatica, including pathophysiology and causes, as well as red flag symptoms of sciatica, its diagnosis and sciatica treatment. Free Practice Material: https://app.wisdolia.com/deck/XScCpeACwXr0jlY55I9a?r=DnwHGyl95QQgP3ecVSPDHrFGE0E0qB&ref=rhesusmedicine Consider subscribing on YouTube (if you found any of the info useful!): https://w…
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In this week's episode we’ll discuss the safety and efficacy of decitabine in older patients with AML; learn how heme-induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice, and discuss the outcomes of treatment with HLA-mismatched HSCT with TCRab/CD19 lymphocyte depletion or post-HSCT cyclophosph…
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Chronic cough causes explained, looking at the differential diagnosis of a chronic cough as well as treatment options. Includes red flag symptoms associated with chronic cough. Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1 Patreon: https://www.patr…
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In this week's episode we'll discuss minimal residual disease as an intermediate clinical endpoint for multiple myeloma. Then, we'll learn about IPSS-R downstaging before transplant in MDS. Finally we'll hear about the connection between hereditary angioedema and venous thromboembolism. Featured Articles: EVIDENCE meta-analysis: evaluating minimal …
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Interview with Robert D. Gibbons, PhD, and Ronald C. Kessler, PhD, authors of Social Vulnerability and Prevalence and Treatment for Mental Health and Substance Use Disorders. Hosted by John Torous, MD, MBI. Related Content: Social Vulnerability and Prevalence and Treatment for Mental Health and Substance Use Disorders…
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In this week's episode we’ll discuss the safety and efficacy of acalabrutinib, venetoclax and obinutuzumab in relapsed/refractory CLL; learn more about alternative donor transplantation for severe aplastic anemia and discuss clonal relapse dynamics in acute myeloid leukemia following allogeneic hematopoietic cell transplantation. Featured Articles:…
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Dr Adrian Owen joins Sarah Passey to chat about a his Personal View, published in the August 2024 issue of The Lancet Neurology, about detecting awareness after an acute brain injury. Continue this conversation on social! Follow us today at... https://twitter.com/thelancet https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljo…
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A summary of the main contraceptive methods including the pill, mini pill, implant, injection and intrauterine devices. Also includes a classification to make them easier to remember. We also cover the main features of each and general contraindications. Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com…
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In this week's episode we'll learn about the clinical benefit of complete remission with partial hematological recovery, or CRh, in patients with Acute Myeloid Leukemia (AML) treated with molecularly targeted drugs. Then we'll hear about a large cohort of patients with PNH were studied to detail PNH-related thrombotic events, unravel determinants o…
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In this week's episode we’ll discuss the mutational and transcriptional landscape of pediatric BCP lymphoblastic leukemia; learn more about the role of platelet-derived TGF-β1 in immune thrombocytopenia; and discuss the findings from a phase 3 trial of mavorixafor in WHIM syndrome. Featured Articles: Mutational and transcriptional landscape of pedi…
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Aortic Stenosis explained clearly, including pathophysiology and causes. Also features the aortic stenosis murmur sound, and treatment including TAVI vs SAVR. Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1 Patreon: https://www.patreon.com/rhesusmedi…
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Introduced by Associate Editor Robert Zeiser, this Review Series focuses on the problem of immune escape by acute myeloid leukemia (AML). The series opens with a review of how AML escapes T-cell–driven elimination and then focuses on how p53 function impinges on AML recognition by immune cells. The series finishes with a summary of new approaches t…
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In this week's episode we'll discuss new insights on the role of GM-CSF in establishing immune memory. The authors propose that the coordination of opposing immune memory programs, driven by GM-CSF, may be essential to efficient, yet controlled, innate immune responses. After that: Interleukin-1 inhibition in TTP. Researchers explore the potential …
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Acute Sore Throat explained, including different causes including strep throat and peritonsillar abscess, with treatment of each. Also includes common associated symptoms as well as more worrying symptoms and a viral vs bacterial scoring system for acute sore throat. Consider subscribing on YouTube (if you found any of the info useful!): https://ww…
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In this week's episode we’ll discuss the prognostic value of the Chronic Lymphocytic Leukemia International Prognostic Index in the era of targeted therapies, learn how peak ADAMTS13 activity can be used to assess ADAMTS13 conformation and risk of relapse in immune-mediated thrombotic thrombocytopenic purpura, and discuss the findings from a phase …
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In this week's episode we'll discuss assessing risk profile in Wiskott-Aldrich Syndrome, or WAS. Then, we'll learn about how the loss of DNMT3A confers resistance to interferon-alpha in hematopoietic stem cells carrying the JAK2-V617F mutation. Finally, we'll explore unrelated donor selection for AML patients undergoing hematopoietic stem cell tran…
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Dr Glenn Nielsen joins Lauren Southwell to discuss the Physio4FMD trial of specialist physiotherapy for people with functional motor disorder in England and Scotland. This Article is published in the July issue of The Lancet Neurology. Continue this conversation on social! Follow us today at... https://twitter.com/thelancet https://instagram.com/th…
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Interview with Vadim Zipunnikov, PhD, author of Integrative Modeling of Accelerometry-Derived Sleep, Physical Activity, and Circadian Rhythm Domains With Current or Remitted Major Depression. Hosted by John Torous, MD, MBI. Related Content: Integrative Modeling of Accelerometry-Derived Sleep, Physical Activity, and Circadian Rhythm Domains With Cur…
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Systematic approach to taking a good medical history, including example structure. Also includes key questions and information to ask, as well as generating a differential and management plan. Free Practice Material: https://app.wisdolia.com/deck/G5TCwMXZ8xZEXipwAtoG/sepsis-flashcards-multiple-choice-questions-quiz?r=DnwHGyl95QQgP3ecVSPDHrFGE0E0qB&…
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In this week's episode we’ll discuss the safety and efficacy of nilotinib with or without cytarabine in Philadelphia-positive acute lymphoblastic leukemia; learn more about thrombosis risk in double heterozygous carriers of Factor V Leiden and prothrombin G20210A and discuss the utility of circulating cell-free tumor DNA in prognostic prediction in…
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In this week's episode we'll learn about fitusiran prophylaxis in patients with hemophilia A or B, with or without inhibitors. Next we'll hear about new findings that heterozygous germline variants in the NBN gene that are linked to increased risk of B-cell acute lymphoblastic leukemia in children. Finally, we'll explore new insights on the histone…
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Interview with Tom Bschor, MD, author of Differential Outcomes of Placebo Treatment Across 9 Psychiatric Disorders: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD, MBI. Related Content: Differential Outcomes of Placebo Treatment Across 9 Psychiatric Disorders
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