#11 Junho 2024 - PREOXI, Doente Crítico & Outros

Hipótese Nula

TEMA PRINCIPAL:

Noninvasive Ventilation for Preoxygenation during Emergency Intubation - PREOXI | NEJM

» VNI na EOT emergente deve passar a 1ª-linha? Diz-nos o que achas

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REVISÕES SISTEMÁTICAS de ECAs

Diagnóstico e Raciocínio Clínico

✔✔✔ Randomised controlled trials evaluating AI in clinical practice: scoping review | Lancet Digital Health

Doente crítico/urgente

??? Proton-Pump Inhibitors to Prevent Gastrointestinal Bleeding — An Updated Meta-Analysis | NEJM Evidence

✗✗✗ A Patient-Level Meta-Analysis of Intensive Glucose Control in Critically Ill Adults | NEJM Evidence

Geral, Geriatria & Paliativos

✔✔✔ Ultrasound-guided central venous catheterization around the neck: Systematic review & n-meta-analysis | AJEM

Infecciologia, Microbiologia & Antimicrobianos

??? Prolonged vs Intermittent Infusions of β-Lactam Antibiotics in Adults With Sepsis or Septic Shock | JAMA

ENSAIOS CONTROLADOS E ALEATORIZADOS

Doente crítico/urgente

✔✔✔ Noninvasive Ventilation for Preoxygenation during Emergency Intubation - PREOXI | NEJM

✔ Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation - REVISE | NEJM

Infecciologia, Microbiologia & Antimicrobianos

??? Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis - The BLING III | JAMA

✗✗✗ Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection - STOP-PASC

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REVISÕES SISTEMÁTICAS COM ESTUDOS OBSERVACIONAIS (com ou sem ECA)

Nefrologia

✔✔✔ SGLT2i and the risk for dialysis and cardiovascular disease in patients with stage 5 chronic kidney disease | AIM

Oncologia

✔✔✔ Red Flag Signs and Symptoms for Patients With Early-Onset Colorectal Cancer | JAMA Network Open

PRIMÁRIOS - SUB-ANÁLISE / COORTE / CASO-CONTROLO / INQUÉRITOS / A. ECONÓMICAS

Cirurgia, Ortopedia & MFR

✔✔✔ Cost-effectiveness of craniotomy vs decompressive craniectomy for traumatic acute subdural haematoma | BMJ Open

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