Our channel provides longevity, anti-aging and health information. We interview experts in their field to get the latest information in the longevity space. You can also come to our YouTube channel for more information here https://www.youtube.com/channel/UCLFEKx_LchTLy_XwjPToJ3A
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Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it. The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than second ...
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"The Art of Living Proactively" podcast is your guide to harnessing the power of your choices and living your best life. Join host Tony Winyard as he shares insights and inspiration from experts in the fields of health, wellness, mindset, and productivity. Each episode offers practical tips and strategies to help you take control of your life and unlock your full potential. From improving your physical health to cultivating a positive mindset, Tony and his guests explore the habits and pract ...
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How To Activate Your Stem Cells For Rejuvenation | Christian Drapeau Interview
1:10:13
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Here we talk Christian Drapeau founder of Stemregen about the wonders of stem cells. We dive into the science of what they are, how they work to repair the body and how we can mobilize them to help us remain healthy. 🌐Links in this Interview Stemregen home page https://www.stemregen.co/ Stemregen 15% discount Code MODERN https://tinyurl.com/45z968y…
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Ancestral vs. Modern Human Diets, Seed Oils, Inflammation, Fat Oxidation, Influence of Industry on Food Science | Steven Rofrano | IS #3
1:33:42
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1:33:42
Send us a text Special episode: Episodes in the Independent Scholars (IS) series are available in full to paid subscribers on the M&M Substack. This is a free, partial version. About the guest: Steven Rofrano became interested in human health & food, including ancestral vs. modern diets, from personal experiences in diet & allergies during college.…
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Bad Science, Nutrition Epidemiology, History of Obesity Research, Diet & Metabolic Health | Gary Taubes | #176
1:42:23
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1:42:23
Send us a text About the guest: Gary Taubes is a researcher, science historian, and science journalist. He has written several books, including “Rethinking Diabetes.” Episode summary: Nick and Gary Taubes discuss: the field of nutrition epidemiology and why it’s filled with so much junk science; social factors influencing scientific research; the h…
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Aging, Biological Clocks, Proteomics, Longevity & Healthspan | Austin Argentieri | #175
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1:33:17
Send us a text About the guest: Austin Argentieri, PhD is a researcher in the Analytic & Translational Genetics Unit at the Massachusetts General Hospital with academic appointments at Harvard & the Broad Institute. His research focuses on large-scale analyses to to understand human aging. Episode summary: Nick and Dr. Argentieri discuss: chronolog…
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Adipose Tissue & Body Fat: Obesity, Insulin, Leptin, Fertility, Weight Loss & GLP-2 Drugs | Sean Hartig | #174
1:43:52
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1:43:52
Send us a text About the guest: Sean Hartig, PhD is an associate professor at the Baylor College of Medicine, where is lab studies adipose (fat) tissue, metabolic regulation, and obesity & energy balance disorders. Episode summary: Nick and Dr. Hartig discuss: visceral vs. subcutaneous fat; white, brown, and beige adipose tissue; physiology of fat …
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How The Science of HRV Can Extend Your Healthy Longevity | Dr Torkil Færø Interview
1:04:47
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Apologies for the delay in releasing this. Should be more regular in the future! DESCRIPTION Here we talk with Dr Torkil Færø the author of the Pulse Cure about what HRV is, how it is linked to health and how we can use it to improve our longevity protocol 🌐Links in this Interview The Pulse Cure website with lecture from Dr Færø https://thepulsecur…
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Psychedelics, Consciousness, Psychiatry, Psychology, Mental Health & the Entropic Brain Hypothesis | Robin Carhart-Harris | #173
1:57:41
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1:57:41
Send us a text About the guest: Robin Carhart-Harris, PhD is a neuroscientist & psychopharmacologist. His lab at the University of California-San Francisco studies the effects of psychedelics and other drugs on the human brain, using neuroimaging and other approaches. Episode summary: Nick and Dr. Carhart-Harris discuss: psychedelics & the human br…
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Immune System, Gut Microbiome, Vitamin D, Cancer, Innate Immunity, Inflammation & Gut-Immune Interactions | Caetano Reis e Sousa | #172
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1:12:05
Send us a text About the guest: Caetano Reis e Sousa, DPhil is an immunologist and Principal Group Leader at the Francis Crick Institute in London. His lab studies immune system function, including its ability to fight infection and cancer. Episode summary: Nick and Dr. Reis e Sousa discuss: dendritic cells & innate immunity; how the immune system …
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Comparative Brain Evolution: Mammals, Primates & Humans | Robert Barton | M&M #171
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1:38:48
Send us a text About the guest: Robert Barton, PhD is an evolutionary anthropologist and Professor at Durham University. He studies the evolution of the brain and behavior across species, including humans. Episode summary: Nick and Dr. Barton discuss: mammalian brain evolution; how brain and body size scale across mammals; how metabolism relates to…
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Sex Differences, Drugs & the Brain: Psychedelics, Psilocybin, Alcohol & Nicotine | Melissa Herman | #170
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1:15:21
Send us a text About the guest: Melissa Herman, PhD is a neuroscientist and associate professor at the University of North Carolina. Her lab studies the effects of drugs on the brain and behavior in rodents. Episode summary: Nick and Dr. Herman discuss: sex differences in the brain between males and females; behavioral variability among individuals…
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Epigenetics, Chromatin Plasticity & the Neural Basis of Memory | Giulia Santoni | M&M #169
1:23:45
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1:23:45
Send us a text About the guest: Giulia Santoni, PhD is a neuroscientist who obtained her PhD at the EPFL in Switzerland, where she studied epigenetic influences on memory formation. Episode summary: Nick and Dr. Santoni discuss: transcription & gene regulation; synaptic plasticity; learning & associative memory; epigenetics, histones, DNA methylati…
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Sleep: Neural Circuits, Orexin/Hypocretin, Hypothalamus, Neuromodulators, Stress & Cortisol, Sleep Drugs & Ultrasound Technology | Luis de Lecea | #168
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1:39:31
Send us a text About the guest: Luis de Lecea, PhD is a neurobiologist whose lab at Stanford University studies the neural basis of sleep & wakefulness in animals. Episode summary: Nick and Dr. de Lecea discuss: the neural basis of sleep; sleep architecture & sleep phases (NREM vs. REM sleep); orexin/hypocretin neurons & the lateral hypothalamus; c…
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The Science Of Balancing A Diet For Longevity | Drs Steve Simpson & Dave Raubenheimer
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Here we talk with Dr Steve Simpson and Dave Raubenheimer about their concept of Nutritional Geometry and how this helps to think about the optimal macro and micro nutrient mix. Of particular note is Protein Leverage, the idea that humans will eat until we have had sufficient protein. 🌐Links in this Interview Charles Perkins Centre https://www.sydne…
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Plant Chemistry & the Chemical Basis of Marijuana Aroma | Iain Oswald | #167
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51:09
Send us a text About the guest: Iain Oswald, PhD is an organic chemist and Director of Research & Development at Abstrax Tech. Episode summary: Nick and Dr. Oswald discuss: plant chemistry; marijuana strains and their aroma; the chemical basis of cannabis aroma; terpenes vs. non-terpene volatile organic compounds; and more. Related episodes: Mariju…
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Reverse Aging By Changing Your Thoughts! | Dr Ellen Langer Interview
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1:02:08
Here we talk with Professor Ellen Langer of Harvard University about her research and her latest book, The Mindful Body : Thinking Our Way To Chronic Health. The mind and body are one and we can control the body with the mind. 🌐Links in this Interview Dr Langer page at Harvard https://psychology.fas.harvard.edu/people/ellen-langer Home page https:/…
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History of Diet & Food, Population Density & Social Stability, Psychological Pandemics, Physical & Mental Health in Civilizational Cycles | Rudyard Lynch | IS #2
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Send us a text Special episode: Episodes in the Independent Scholars (IS) series are available in full to paid subscribers on the M&M Substack. This is a free, partial version. About the guest: Rudyard Lynch is a history and anthropology scholar and host of the popular YouTube channel, whatifalthist. Episode summary: Nick and Rudyard discuss: histo…
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Foods That Enhance Stem Cells & Longevity | Dr William Li Interview
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1:13:25
Here we talk with Dr William Li about how food can be medicine, both in a preventative and a therapeutic way. We focus mostly on stem cell activation and preservation and also look at angiogenesis - building new blood vessels. 🌐Links in this Interview Dr William Li's website https://drwilliamli.com/ Links to Dr Li's other social channels and his ma…
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Evolution: Natural Selection, Genetic Drift, Origin of Life, Cellular Complexity, Epigenetics | Michael Lynch | #166
1:29:28
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1:29:28
Send us a text About the guest: Michael Lynch, PhD is an evolutionary biologist at Arizona State University who studies the origins of genomic and cellular complexity. Episode summary: Nick and Dr. Lynch discuss: natural selection vs. genetic drift; genetic mutations & the speed of evolution; origin of life; the evolution of cellular complexity; ep…
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PUFAs in Brain Health & Disease, Dietary Fats, Brain Lipids, Nutrition | Richard Bazinet | #165
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1:41:18
Send us a text About the guest: Richard Bazinet, PhD is neurochemist and nutritional scientist at the University of Toronto. His lab studies brain lipid metabolism in health and disease. Episode summary: Nick and Dr. Bazinet discuss: lipid metabolism in the liver and brain; dietary fatty acids (saturated, monounsaturated, polyunsaturated); fatty ac…
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Power Up Your Mitochondria With Red Light Therapy | Dr Glen Jeffery Interview
1:06:29
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1:06:29
Here we talk with Dr Glen Jeffery from University College London about how red light energizes your mitochondria and some of the amazing benefits of this. We also discuss some of the detrimental effects of blue light. 🌐Links in this Interview Dr Jeffery's website https://www.ucl.ac.uk/biosciences/people/prof-glen-jeffery Some papers from Dr Jeffery…
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The Science Behind A Novel Longevity Supplement Blend - NOVOS Vital | Dr Diogo Barardo Interview
1:13:58
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1:13:58
DESCRIPTION Here we talk with Dr Diogo Barardo, who is head of research and development at NOVOS, about NOVOS Vital, a supplement which comes in a gummie form and have a catch-up on other activities at NOVOS. 🌐Links in this Interview NOVOS Labs website https://novoslabs.com/ Drug age database paper The DrugAge database of aging-related drugs https:…
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Seed Oils, Chronic Disease, Diet & Religious Cults, Mainstream Medicine vs. Independent Research | Tucker Goodrich | IS #1
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20:38
Send us a text Special episode: Episodes in the Independent Scholars (IS) series are available in full to paid subscribers on the M&M Substack. This is a free, partial version. About the guest: Tucker Goodrich is an independent researcher and self-described “seed oil zealot” who credits many of his own health improvements with minimizing his consum…
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Dopamine, Reward, Motivation, Lateral Hypothalamus, Feeding Behavior & Eating Disorders | Melissa Sharpe | #164
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1:08:39
Send us a text About the guest: Melissa Sharpe, PhD is a neuroscientist. Her lab at the University of Sydney studies reinforcement and reward learning in rodents. Episode summary: Nick and Dr. Sharpe discuss: dopamine and its association with reward learning and motivation; reinforcement learning & the brain; the lateral hypothalamus and feeding be…
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Anesthesia, Placebo Effects, Consciousness, Subjectivity, MDMA, Ketamine, Opioids, Psychedelics | Boris Heifets | M&M #163
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1:44:35
Send us a text About the guest: Boris Heifets, MD, PhD is an anesthesiologist and researcher at Stanford University. His lab studies non-ordinary states of consciousness and psychoactive drugs like MDMA, ketamine, and psychedelics. Episode summary: Nick and Dr. Heifets discuss: anesthesia and how anesthetics work; placebo effects & expectations in …
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Drugs, Addiction & Neuroplasticity: Psychedelics, MDMA, Opioids, Cocaine, Amphetamine (Adderall), Nicotine, Marijuana & Alcohol | Robert Malenka | M&M #162
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1:34:42
Send us a text About the guest: Robert Malenka, MD, PhD is psychiatrist & neuroscientist. He has spent most of his career at Stanford University, where his lab studies synaptic plasticity, mechanisms of drug action in the brain, and the neural basis of behavior. Episode summary: Nick and Dr. Malenka discuss: mechanisms of synaptic plasticity in the…
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GLP-1, Weight Loss Drugs, Ozempic, Obesity, NMDA Receptors, Metabolism & Brain Health | Christoffer Clemmensen | #161
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1:32:36
Send us a text About the guest: Christoffer Clemmensen, PhD is scientist running the Metabolism & Molecular Pharmacology group at the University of Copenhagen in Denmark. His lab studies the biological basis of obesity & other metabolic disorders. Episode summary: Nick and Dr. Clemmensen discuss: GLP-1 & gut hormones; obesity & metabolic disease; G…
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Age Reversal & Thymus Rejuvenation TRIIM-X 2024 Update | Dr Greg Fahy Full Interview
1:15:38
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1:15:38
DESCRIPTION Dr. Greg Fahy is a world renowned cryobiologist and is also the chief science officer, and co-founder, of Intervene Immune, a company which pioneers treatments for thymus regeneration and age-related immune system decline. Dr. Fahy Designed and led the pilot TRIIM trial which first time showing both thymus rejuvenation and reversal of h…
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Diet, Hunting, Culture and Evolution of Paleolithic Humans & Hunter Gatherers | Eugene Morin | #160
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1:24:10
Send us a text About the guest: Eugene Morin, PhD is a Professor of Anthropology at the University of Trent who studies Paleolithic humans and animals. Episode summary: Nick and Dr. Morin discuss evolution of Paleolithic humans; Neanderthal diet & cultural capacity; key human adaptations related to endurance and stamina; hunter gatherer hunting str…
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Neuroscience of Social Behavior, Pain, Empathy, Emotion, Brain Mechanisms of MDMA | Monique Smith | #159
1:26:45
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1:26:45
Send us a text About the guest: Monique Smith, PhD is an assistant professor of neurobiology at the University of California-San Diego, where her lab studies the neuroscience of social behavior, pain, and emotion. Episode summary: Nick and Dr. Smith discuss: the neurobiology of pain perception; social & empathy-like behavior in animals; emotion; br…
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The Most Promising Rejuvenation Therapy Now In Clinical Trials | Dr Hans Keirstead Full Interview
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1:03:45
Description Hi all, apologies for the erratic release schedule recently. We have now changed the way that we release interviews on our YouTube channel and from now on will post the whole interview in a single video. The podcasts will follow the same pattern. This will mean that we have fewer, though longer podcasts. I hope that this works for you a…
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Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino | #158
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1:41:30
Send us a text About the guest: Dominic D'Agostino, PhD is a researcher and professor at the University of South Florida, where his lab studies metabolism, human biology, and related subjects. Episode summary: Nick and Dr. D'Agostino discuss: ketosis and the ketogenic diet; effects of ketosis on diabetes, insulin resistance & metabolic health; effe…
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Nitric Oxide The Miracle Molecule For Longevity | Dr Nathan Bryan Full Interview
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59:44
Hi all, apologies for the erratic release schedule recently. We have now changed the way that we release interviews on our YouTube channel and from now on will post the whole interview in a single video. The podcasts will follow the same pattern. This will mean that we have fewer, though longer podcasts. I hope that this works for you all. Thanks R…
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Preventative Medicine, Diet & Lifestyle vs. Pharmaceuticals in Health & Disease, Lies Taught in Medical Schools | Robert Lufkin | #157
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1:45:15
Send us a text About the guest: Robert Lufkin, MD is a radiologist and professor at UCLA. His new book is called, "Lies I Taught in Medical School." Episode summary: Nick and Dr. Lufkin talk about: the history of medicine in the United States; diet & lifestyle vs. pharmaceuticals in acute vs. chronic disease; diabetes, metabolic syndrome & insulin …
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My Longevity Protocol | Dr Carolina Reis Ep 5/5
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16:49
Here Dr Reis talks about what causes aging of the skin, and UVB is one of the main causes and what her longevity protocol looks like. Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem cell and tissue engineering. After more than 10 years of developing science in academia, …
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Psychology of Stress, Resilience, Emotion & Child Development | Stephen Sideroff | #156
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1:39:59
Send us a text About the guest: Stephen Sideroff, PhD is a clinical psychologist and Associate Professor of Psychiatry and Behavioral Sciences at UCLA. His new book is, "The 9 Pillars of Resilience." Episode summary: Nick and Dr. Sideroff discuss: childhood & developmental psychology; clinical & Gestalt psychology; stress & resilience; pharmaceutic…
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OneSkin Customer Feedback | Dr Carolina Reis Ep 4
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Here Dr Reis talks about some of the customer feedback that they have received. The feedback is available at the bottom of the product pages on the OneSkin website. Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem cell and tissue engineering. After more than 10 years of d…
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Cell Biology of Aging, Mitochondria, Metabolism, Autophagy & Stress | Andrew Dillin | #155
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1:39:45
Send us a text About the guest: Andrew Dillin, PhD is Professoer of Molecular & Cell Biology at UC-Berkeley and Howard Hughes Medical Institute investigator. His lab studies mechanisms of aging, mitochondrial biology, and related subjects. Episode summary: Nick and Dr. Dillin discuss: cell biology; mitochondria & the endoplasmic reticulum; aging & …
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OneSkin Human Trial Results | Dr Carolina Reis Ep 3
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11:46
Here Dr Reis talks about the human as well as in vitro trials that her company is doing. The papers can be found on the OneSkin website (including the one that she refers to in the video as being published in the next week) Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem…
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The Science of Youthful Skin : Unveiling OneSkin’s New Antiaging Series | Dr Carolina Reis Ep 2
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Here Dr Reis talks about the new series of products that the team at OneSkin have developed, including for body, eyes, sun protection and a cleanser. Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem cell and tissue engineering. After more than 10 years of developing scien…
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Evolution & Genetics of Human Diet, Metabolism, Disease Risk, Skin Color & Origins of Modern Europeans | Eske Willerslev | M&M #154
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1:52:23
Send us a text About the guest: Eske Willerslev, PhD is an evolutionary biologist and Professor of evolution at both the University of Copenhagen and University of Cambridge. Episode summary: Nick and Dr. Willerslev discuss: human evolution out of Africa; the origins of modern Europeans; hunter gatherers, early farmers, and pastoralists; genetics o…
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Reverse Skin Aging With Science | Dr Carolina Reis OneSkin Ep 1
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11:06
Here Dr Reis talks about the development of OS-1 the peptide used in One Skins products, its senomorphic effects and other ingredients which are included in the One Skin product range. Dr. Carolina Reis is the co-found and CEO of OneSkin Technologies. She holds a biochemistry degree and a Ph.D. focused on stem cell and tissue engineering. After mor…
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Diet, Nutrition, Metabolic Psychiatry, Brain & Mental Health | Georgia Ede | #153
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1:51:27
Send us a text About the guest: Georgia Ede, MD is a psychiatrist and author of, "Change Your Diet, Change Your Mind: A Powerful Plan to Improve Mood, Overcome Anxiety, And Protect Memory for a Lifetime of Optimal Mental Health." Episode summary: Nick and Dr. Ede discuss: glucose vs. ketones for brain energy; metabolic health & insulin resistance; …
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A Guide to Protein for Optimal Results | Dr Jorn Trommelen Ep 5/5
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19:15
Here Dr Trommelen talks about practical take aways from his study. How much protein should we eat, how often and what type is best. He also talks about his personal protocol. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Department of Human Biology at Maastricht University. He is involved in research and education …
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Plant Chemistry, Cannabinoids, Cannabis Terpenes & the Entourage Effect | Ryan Vandrey | #152
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1:30:43
Send us a text About the guest: Ryan Vandrey, PhD is a Professor of Psychiatry & Behavioral Sciences at Johns Hopkins University, where his lab studies the behavioral pharmacology of cannabis (marijuana), nicotine/tobacco, and other substances. Episode summary: Nick and Dr. Vandrey discuss: marijuana; cannabinoids like THC; terpenes like limonene, …
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The Unexpected Role Of mTOR In Muscle Building | Dr Jorn Trommelen Ep 4
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12:19
Here Dr Trommelen talks about how the MPS continues for more than 12 hours, because of the presence of amino acids in the blood, however, mTOR does not appear to be activated and autophagy is not suppressed and provides his explanation for these findings. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Department of …
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Aging, mTOR, Sirtuins, Rapamycin, Metformin, the Truth of Resveratrol & Longevity Supplements, David Sinclair & Anti-Aging Myths | Matt Kaeberlein | #151
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2:28:31
Send us a text About the guest: Matt Kaeberlein, PhD is a Professor of at the University of Washington and CEO of OptiSpan. His research focuses on the biology of aging and longevity. Episode summary: Nick and Dr. Kaeberlein discuss: the biology of aging; mTOR, FGF1, growth & metabolism; sirtuins, NAD & NMN; longevity drugs like metformin & rapamyc…
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The Science Of Muscle Synthesis & Protein Turnover | Dr Jorn Trommelen Ep 3
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19:24
Here Dr Trommelen talks about the amount of protein required to initiate MPS, what muscle break down is and how MPS is measured. Key take away: It is muscle synthesis which determines muscle mass much more then breakdown as breakdown remains in a very tight range. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Depar…
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Visual System, Visual Impairments & Cures, Amblyopia, Neuroplasticity, Critical Periods & Metaplasticity, Ketamine & Psychedelics | Mark Bear | #150
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1:16:10
Send us a text About the guest: Mark Bear, PhD is a Professor of Neuroscience at MIT, where his lab studies the visual system, neuroplasticity, and the pathophysiology of amblyopia and visual impairments. Episode summary: Nick and Dr. Bear discuss: the visual system in the brain, from the retina to visual cortex; critical periods of brain developme…
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Optimize Exercise & Protein Intake For Muscle Growth | Dr Jorn Trommelen Ep 2
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14:42
Here Dr Trommelen talks about exercise and protein and how they are related to muscle protein synthesis. The importance of having both, the time window for MPS and the training stimuli required. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Department of Human Biology at Maastricht University. He is involved in res…
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New Study Shows No Upper Limit For Protein In Building Muscle | Dr Jorn Trommelen Ep 1
13:22
13:22
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Curtido
13:22
Here Dr Trommelen talks about the background to the study, the major results and the type of protein used. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Department of Human Biology at Maastricht University. He is involved in research and education regarding the impact of exercise and nutrition on muscle mass and fu…
…
continue reading